Oxidative Stress and Inflammation Biomarkers in Acute Pancreatitis

Cerulein pancreatitis: oxidative stress, inflammation, and apoptosis.

Cerulein pancreatitis is similar to human edematous pancreatitis, manifesting with dysregulation of digestive enzyme production and cytoplasmic vacuolization, the death of acinar cells, edema formation, and infiltration of inflammatory cells into the pancreas. Reactive oxygen species are involved in nuclear factor-kappaB activation, cytokine expression, apoptosis and pathogenesis of pancreatiti...

Time course changes of oxidative stress and inflammation in hyperoxia-induced acute lung injury in rats

Objective(s):Therapies with high levels of oxygen are commonly used in the management of critical care. However, prolonged exposure to hyperoxia can cause acute lung injury. Although oxidative stress and inflammation are purported to play an important role in the pathogenesis of acute lung injury, the exact mechanisms are still less known in the hyperoxic acute lung injury (HALI).   Materials ...

Some acute phase proteins, oxidative stress biomarkers and antioxidant enzyme activities in ewes with pregnancy toxemia

The aim of this study is to investigate antioxidant enzymes, oxidative stress biomarkers and the acute phase proteins levels for subclinical and clinical pregnancy toxemia and to determine the effect of early diagnosis on the success of curing. According to the results of clinical and biochemical parameters, from 39 ewes, 10 were healthy ewes (control group), 13 ewes had subclinical pregnancy t...

Oxidative Stress and Cellular Adhesion Molecules in Acute Pancreatitis

Association between the circulating leptin levels and the biomarkers of oxidative stress and inflammation among Iranian overweight and obese adults

Background: Oxidative stress in obese people is an important pathogenic mechanism of an obesity-associated metabolic syndrome. We evaluated the association between circulating leptin levels with biomarkers of oxidative stress in overweight and obese participants.    Methods: This study was performed on 189 overweight and obese people aged 18-60 years old. Serum leptin, superoxide dis...